Taking Blood Pressure Drugs at Bedtime May Boost Effectiveness

(HealthDay News) — Taking blood-pressure pills at night, rather than in the morning, may better control hypertension and significantly reduce the risk of heart attack and stroke, new research suggests.

The results of the five-year study add to the growing evidence that tailoring the timing and dosage of medications to the body’s biological rhythms may help drugs work better and with fewer side effects, the researchers said.

The research also highlighted the importance of sleep-time blood pressure, the most sensitive predictor of a person’s risk of death from cardiovascular disease over a five-year period.

In healthy people, blood pressure dips at night, by 10 percent to 20 percent. “Nondippers,” whose blood pressure doesn’t fall as it should at night, are more vulnerable to cardiovascular events such as heart attack and stroke, the researchers said.

“This study confirms sleep-time blood pressure as the most relevant predictor of cardiovascular risk,” said lead researcher Ramon C. Hermida, director of the bioengineering and chronobiology laboratories at the University of Vigo, Spain.

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